COMPUTATIONAL SYSTEM LEVEL APPROACHES FOR DISCERNING RECIPROCAL REGULATION OF IL10 AND IL12 IN LEISHMANIASIS

IL12 and IL10 are two of the major cytokines which control the fate of Leishmaniasis.This paper presents two models healthy state and diseased state which shows how secretion of IL12 is responsible for Shirts parasite elimination and IL10 can jeopardize the parasite elimination and promote its survival.Epigenetic modification in the host IL12 and I

Mitral valve plasty (MVP) is preferred over mitral valve replacement (MVR) for mitral regurgitation in humans because of its favorable effect on quality of life.In small dogs, it is difficult to repair multiple lesions in both leaflets using MVP.Herein, we report a case of severe mitral regurgitation caused by multiple severe Fridge or Freezer lesi